Pyrigesic 500 Mg Tablet 10

Pyrigesic 500 MG Tablet 10

East India Pharmaceutical Works Ltd.

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Composition

Paracetamol/acetaminophen (500 Mg)

Pyrigesic tablet is an analgesic and antipyretic medication. It is commonly used to reduce pain and fever. It provides effective relief from various types of pain, including headaches, backaches, toothaches, and menstrual cramps.

It is also effective in managing fever associated with common illnesses like common cold and other infectious conditions.

It is important to inform your doctor about any existing medical conditions, ongoing medications and if any side effects occur after the use of this medicine.

The uses of Pyrigesic Tablet are as follows:

Relieving mild to moderate pain: It is used for the management of headaches, musculoskeletal pain, toothaches, backaches.
Reduction of fever: lowers elevated body temperature (fever) often associated with conditions such as common cold, sore throat, or infections.
Pain associated with menstrual periods: It can help reduce the discomfort and pain experienced during menstruation.
Pain from osteoarthritis: Management of pain associated with osteoarthritis, a condition characterized by joint pain and stiffness.
After vaccinations: It may also be used to reduce pain and mild fever that may occur after vaccination.

Directions for Use of Pyrigesic 500 MG Tablet 10

When taking a Pyrigesic tablet, following the instructions provided by your doctor is essential. Here are some general guidelines:

Swallow the Pyrigesic tablet as a whole with a glass of water.
You can take it with or without food, although taking it with food may help prevent stomach upset.
Do not chew, crush, or break the tablet.

Pyrigesic tablet is administered orally.

Side Effects of Pyrigesic 500 MG Tablet 10

Pyrigesic tablets are generally safe and well-tolerated when used correctly. However, like any medication, it may cause some side effects in some individuals. Common side effects of Pyrigesic tablet may include:

Nausea
Vomiting
Upset stomach
Diarrhoea

If any of these side effects persist or worsen, it is essential to consult your doctor. They can guide you to manage these side effects or adjust your dosage if necessary.

Pyrigesic tablet contains Paracetamol/acetaminophen (500 MG) as its active ingredient which acts by:

Inhibiting the Cyclooxygenase enzyme which is responsible for the production of prostaglandins, which in turn are responsible for mediating symptoms like pain and fever.
Thus, by reducing the production of Prostaglandins, it reduces the symptoms caused by them

Pregnancy

Pregnant females should consult their doctor before using this medication. These tablets may be unsafe to use during pregnancy, especially in the later stages. If needed, it should be done in the lowest possible doses on advice of a doctor.

Breastfeeding

Breastfeeding females should consult their doctor before using this medication, as its safety during breastfeeding is not evidenced.

Alcohol

It is unsafe to consume alcohol while taking Pyrigesic tablet as it can increase the side effects associated with this medicine.

Liver

If you have a history of liver disease or currently have liver problems, it is essential to inform your doctor before starting Pyrigesic tablet as this medicine also affects your liver. Your doctor will adjust the dosage or monitor your liver function while you are taking this medication.

Kidney

Patients with kidney disease should use Pyrigesic tablet with caution. Dose adjustments may be necessary in such cases. It is recommended to consult your doctor before taking this medication if you have kidney problems.

Using Machines & Driving

Pyrigesic tablet will not likely affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness as side effects, avoiding driving or using machinery until you feel better is advisable.

Allergy

If you are allergic to paracetamol or any other ingredients present in Pyrigesic tablet, avoiding this medication is essential.

Children

Pyrigesic tablet is generally not recommended for children below 10 years.

Older Patients

For older patients, caution is needed while using Pyrigesic tablets, especially if they have an existing liver or kidney disease. The doctor may prescribe a safe dose based on their age and individual health condition.

Interactions of Pyrigesic 500 MG Tablet 10

Drug-Drug Interactions

Pyrigesic tablets can interact with medications, including:

Metoclopramide and Domperidone: Increase the speed of absorption of Pyrigesic tablet. This can result in faster and potentially higher levels of paracetamol in the bloodstream.
Antibiotics(penicillins) like Flucloxacillin: Taking Pyrigesic tablet and Flucloxacillin together can lead to a condition called high anion gap metabolic acidosis (a condition characterised by increased levels of acid in the body).
Blood thinners like Warfarin - This medication may increase the risk of bleeding associated with Warfarin. It's essential for individuals taking blood thinners to use Pyrigesic tablets cautiously and under the guidance of a doctor.

Drug-Disease Interactions

Pyrigesic tablets may interact with certain diseases, including:

Liver disease: The metabolism of this medication primarily occurs in the liver. In cases of existing liver disease, such as hepatitis or cirrhosis, the liver's ability to process this medicine may be compromised. This can increase the risk of liver damage or failure.
Alcohol use disorder: Chronic and excessive alcohol consumption can also affect liver function. When combined with Pyrigesic tablet, it may increase the risk of liver damage.

If you have any of these conditions, informing your doctor before starting Pyrigesic tablet is vital. They can guide the appropriate dosage or alternative treatment options.

Daily Dose

The recommended daily dose of a Pyrigesic tablet is usually taken as directed by your doctor. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is essential to follow the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

If you or someone else takes an excessive Pyrigesic tablet by accident, seeking immediate medical attention from your doctor or a nearby hospital is essential. Symptoms of an overdose may include nausea, vomiting, extreme tiredness, and loss of appetite. There is a possibility of liver damage in patients with overdose of this medicine, therefore prompt action is warranted.

Missed Dose

If you forget to take a dose of Pyrigesic tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. Always follow the instructions given by your doctor.

To ensure the efficacy and safety of Pyrigesic tablet, it is essential to store it properly:

Store this medicine at room temperature (15-25ºC).
Protect it from light and moisture.
Keep Pyrigesic tablets out of the reach of children.
Do not use this medicine after the expiry date has passed.

In addition to taking Pyrigesic tablet, here are some lifestyle tips that can help manage pain and fever:
Drink an adequate amount of water throughout the day to stay hydrated. This is especially important when you have a fever, as it can help prevent dehydration.
Maintain a balanced diet that includes a variety of fruits, vegetables, whole grains, lean proteins, and healthy fats. A nutritious diet supports overall health and can aid in recovery.
It is advisable to avoid consuming alcohol while taking Pyrigesic tablet. Alcohol can interact with the medication and may increase the risk of liver damage.
Be aware of other medications you are taking, including over-the-counter medicines and supplements. Some medications may interact with Pyrigesic tablets, so consult your doctor to ensure safe use.

Fact Box

Drug Category	Cyclooxygenase inhibitor
Therapeutic Category	Analgesic and antipyretic
Available Dosage Types	Tablets
Habit Forming	No
Ailment	Pain and fever

Is Pyrigesic tablet safe during pregnancy?

Pyrigesic tablets need caution for use in pregnancy. It is essential to consult your doctor and weigh the benefits against the potential risks before taking this medication. If needed, should be used in the lowest possible effective dose.

Can I consume alcohol while taking a Pyrigesic tablet?

It is unsafe to consume alcohol while taking Pyrigesic tablet. Alcohol can increase the side effects associated with this medicine.

Can Pyrigesic tablets be used in older patients?

Caution is needed when prescribing Pyrigesic tablets to older patients, especially those with existing liver or kidney diseases. The doctor may prescribe a safe dose based on their age and individual health condition.

What are the side effects of Pyrigesic tablet?

The common side effects of Pyrigesic tablet may include stomach upset, diarrhea, nausea, and vomiting. If these side effects persist or worsen, it is essential to consult your doctor.

Can Pyrigesic tablet interact with other medications?

Yes, Pyrigesic tablets may interact with certain medications such as Warfarin, Metoclopramide, Domperidone and Flucloxacillin. You must inform your doctor about all your medications to avoid any potential interactions.

Last Updated On 20 Oct. 2023 | 3:37PM (IST)

Manufacturer details

202/203, Syndicates Chamber, 2nd Floor, S N Road, Andheri East, Mumbai, Maharashtra 400069

Country of origin: INDIA

References

Center for Drug Evaluation and Research. Acetaminophen [Internet]. FDA; [cited 2023 Sept 15]. Available from: https://www.fda.gov/drugs/information-drug-class/acetaminophen
Acetaminophen: Medlineplus Drug Information [Internet]. U.S. National Library of Medicine; [cited 2023 Sept 12]. Available from: https://medlineplus.gov/druginfo/meds/a681004.html
Paracetamol (no date) Paracetamol 500mg Tablets - Summary of Product Characteristics (SmPC) - (emc). Available at: https://www.medicines.org.uk/emc/product/5164/smpc
Acetaminophen: CDSCO. Gov.in. [cited 2023 Jul 12]. Available from: https://cdscoonline.gov.in/CDSCO/Drugs
DailyMed - ACETAMINOPHEN tablet (no date) U.S. National Library of Medicine. Available at: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c3b408ff-f47b-4fee-ade5-5db6e25f4ee0

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