Zenflox Plus 200/200 MG Tablet 10

Here are the side effects of Zenflox Plus Tablet:

• Nausea: Some individuals may experience a feeling of sickness or queasiness.
• Vomiting: In some cases, the medication may trigger episodes of vomiting.
• Diarrhoea: Having loose or watery stools is common while taking Zenflox Plus.
• Abdominal Pain: Mild to moderate abdominal discomfort or pain may occur.
• Headache: Some individuals may experience mild to moderate headaches.
• Dizziness: Zenflox Plus can cause a feeling of lightheadedness or dizziness.
• Flatulence: Increased gas production and flatulence may be a side effect.

Managing the Side Effects

Here are home remedies that may help manage the side effects of Zenflox Plus Tablet:

• Nausea: Consume ginger in various forms, such as tea or candies. Ginger has natural anti-nausea properties and may help alleviate symptoms. Sip on clear fluids like water, herbal tea, or clear broths to prevent dehydration.
• Vomiting: Drink water, soups, or electrolyte solutions to replenish fluids lost through vomiting. Stick to a bland diet and gradually reintroduce solid foods once vomiting subsides.
• Diarrhoea: Follow the BRAT diet consisting of bananas, rice, applesauce, and toast. These food items are gentle on the stomach and help firm up stools. Consider taking over-the-counter probiotic supplements or consuming probiotic-rich foods like yoghurt to restore the balance of healthy gut bacteria.
• Abdominal Pain: Placing a warm compress or heating pad on the abdomen can relieve stomach pain or cramps. Consider using over-the-counter antacids to help neutralise stomach acid and alleviate pain.
• Headache: Rest in a quiet, dark room and avoid activities that may worsen the headache. Drink plenty of fluids to prevent dehydration.
• Dizziness: If you are experiencing dizziness, avoid activities requiring mental alertness or physical coordination until the symptoms subside.
• Flatulence: Drink peppermint to soothe the digestive system and alleviate flatulence. Avoid gas-producing foods like beans, lentils, carbonated drinks, and certain vegetables like broccoli and cabbage.

Precautions

Pregnancy

Due to the lack of adequate and well-controlled studies on the use of Zenflox Plus Tablets in pregnant women,, it is recommended to use Zenflox Plus Tablets cautiously during pregnancy.

Breastfeeding

Zenflox Plus Tablet should be used with caution during breastfeeding. Zenflox Plus Tablets may pass into breast milk and cause harm to the nursing baby. Therefore, avoiding using Zenflox Plus Tablet during breastfeeding is advisable.

Alcohol

The consumption of alcohol should be avoided when using Zenflox Plus Tablet as it may increase the risk of specific side effects such as dizziness, drowsiness, and liver damage.

Liver

If you suffer from liver problems, use Zenflox Plus Tablet cautiously, as it may raise the levels of liver enzymes. Zenflox Plus Tablet should be taken only under the supervision of a healthcare provider as it may raise the risk of liver damage.

Kidney

Zenflox Plus Tablet is eliminated through urine after being filtered by the kidney. A damaged kidney can cause buildup and toxicity. As a result, use caution when taking Zenflox Plus Tablet, as it may raise the risk of kidney damage. Dose adjustment may be needed.

Using machines and driving

Zenflox Plus Tablet may lead to dizziness or confusion. Do not drive a vehicle or operate machinery after taking this medicine.

Allergy

Patients with a known allergy to Cefixime, Ofloxacin, other quinolone or cephalosporin antibiotics or other ingredients should not use Zenflox Plus Tablet. Inform your doctor and seek emergency medical assistance.

Use in children

Zenflox Plus Tablet is not recommended for children and adolescents under 18. Consult your child's doctor for advice.

Use in older patients

Older patients (60 years and older) may be more sensitive to the effects of Zenflox Plus Tablet, requiring a lower dose or more frequent monitoring. It is essential to inform a healthcare provider of any age-related concerns before taking Zenflox Plus Tablet.

Interaction

Drug-Drug Interactions

Zenflox Plus Tablet can interact with other medications, including:

• Vaccines (Typhoid, Cholera, BCG): Zenflox Plus tablet may interfere with the effectiveness of vaccines. Consult with a healthcare professional regarding the appropriate timing of vaccinations. It is recommended to avoid live vaccines during treatment with Zenflox Plus. The use of inactivated or killed vaccines may be preferred.
• Antiepileptic: Carbamazepine may reduce the concentration of Ofloxacin in the blood, potentially reducing its effectiveness. Close monitoring of therapeutic response and adjustment of the dosage of either medication may be necessary.
• Blood Thinner: Ofloxacin can increase the anticoagulant effects of warfarin, leading to an increased likelihood of bleeding. Regular monitoring of blood clotting parameters and adjustment of the warfarin dosage may be required simultaneously with Zenflox Plus.
• Antacids and ulcer treating medicines: Medications like Aluminium Hydroxide, Magnesium Hydroxide, Cimetidine, and Sucralfate containing aluminium, magnesium, or cimetidine may decrease the absorption of cefixime. To avoid potential interactions, administering Zenflox Plus and antacids/ulcer treating medicines at least 2 hours apart is recommended.
• Medicine to treat excess uric acid: Probenecid may interfere with eliminating cefixime, leading to increased levels of cefixime in the blood. When used together, close monitoring of Cefixime levels and possible dosage adjustments may be necessary.
• Medicines for Arthritis (Methotrexate): Cefixime may decrease the elimination of methotrexate, potentially increasing its toxicity. Regular monitoring of methotrexate levels and adjustment of the dosage may be necessary when using Zenflox Plus with methotrexate.
• Diuretics/Water Pills: Co-administration of furosemide and Zenflox Plus may increase the risk of developing disturbances in the balance of electrolytes, such as low potassium levels. Regular monitoring of electrolytes and kidney function is recommended.
• Asthma Medicine: Ofloxacin may inhibit the metabolism of theophylline, leading to increased theophylline levels in the blood. Close monitoring of theophylline levels and dosage adjustment may be necessary when used simultaneously with Zenflox Plus.
• Pain Killers: Nonsteroidal anti-inflammatory drugs (NSAIDs) such as fenbufen or ibuprofen with Zenflox Plus may increase the risk of developing central nervous system (CNS) stimulation or seizures. Caution should be exercised, and CNS effects should be monitored.

Drug-Food Interactions

Zenflox Plus Tablet can interact with foods, including:

• Dairy products: Dairy products, such as milk, cheese, and yoghurt, may decrease cefixime absorption. Taking Zenflox Plus at least 2 hours before or after consuming dairy products is recommended to avoid potential absorption interference.
• Calcium-rich foods and supplements: Calcium-rich foods and supplements can reduce the absorption of cefixime. It is advisable to separate the administration of Zenflox Plus tablets and calcium-rich foods or supplements by at least 2 hours to prevent decreased effectiveness.
• Iron-rich foods and supplements: Iron-rich foods and supplements can impair cefixime absorption. Taking a Zenflox Plus tablet at least 2 hours before or 2 hours after consuming iron-rich foods or supplements is recommended to avoid potential interaction.
• Caffeine and caffeinated beverages: Caffeine may increase the possibility of experiencing nervous system side effects, such as restlessness and anxiety, associated with the use of Ofloxacin. It is advisable to moderate the consumption of caffeine-containing products while using Zenflox Plus.
• Alcohol: Consumption of alcohol may increase the risk of side effects associated with Ofloxacin, such as dizziness, drowsiness, and impaired judgement. It is recommended to avoid or limit alcohol intake during Zenflox Plus treatment.
• Grapefruit Juice: Grapefruit juice can interfere with the metabolism of Ofloxacin, leading to increased blood levels and potential side effects. It is advisable to avoid consuming grapefruit juice while using Zenflox Plus.

Drug-Disease Interactions

Zenflox Plus Tablet can interact with diseases, including:

• Liver disease: Zenflox Plus Tablet should be used cautiously in patients with liver disease. The liver primarily eliminates cefixime, and a decrease in liver function can lead to higher levels of cefuroxime in the bloodstream, increasing the risk of side effects.
• Colitis: Zenflox Plus Tablet may worsen the signs of colitis, an inflammatory colon condition. Patients with a history of colitis should use Zenflox Plus Tablet with caution, as it may increase the risk of developing antibiotic-associated diarrhoea, which can be severe.
• Kidney disease: Zenflox Plus Tablet should be used cautiously in patients with kidney disease. The dose of Zenflox Plus Tablet may need to be adjusted in patients with severe kidney disease, as cefixime is eliminated primarily by the kidneys.
• Seizure disorders: Patients with a history of seizure disorders such as epilepsy should use Zenflox Plus Tablet carefully, as it can lower the seizure threshold and raise the likelihood of seizures.
• Tendonitis: Fluoroquinolones, including Ofloxacin, have increased the risk of tendonitis and tendon rupture.
• Myasthenia gravis: Zenflox Plus Tablet may aggravate myasthenia gravis symptoms, leading to muscle weakness and fatigue. Patients with myasthenia gravis should be cautious when taking Zenflox Plus Tablet.
• Diabetes: Ofloxacin, one of the active ingredients in Zenflox Plus Tablet, has been associated with an increased risk of hypoglycemia (low blood sugar) in patients with diabetes.